Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax1tm2Neu
Name:	paired box 1; targeted mutation 2, Neuherberg
MGI ID:	MGI:1857741
Synonyms:	Pax1lacZ
Gene:	Pax1  Location: Chr2:147203850-147216972 bp, + strand  Genetic Position: Chr2, 72.63 cM
Alliance:	Pax1tm2Neu page

Germline Transmission:	Earliest citation of germline transmission: J:55575
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: Mice lacking a functional gene were generated by homologous recombination, where a beta galcactosidase gene was introduced within the paired-box encoding exon, resulting in a premature termination of the gene product. (J:55575)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax1 Mutation:	28 strains or lines available

Original:	J:55575 Furumoto TA, et al., Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development. Dev Biol. 1999 Jun 1;210(1):15-29
All:	1 reference(s)