Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Dsg4lah
Name:	desmoglein 4; lanceolate hair
MGI ID:	MGI:1856929
Gene:	Dsg4  Location: Chr18:20569232-20604878 bp, + strand  Genetic Position: Chr18, 11.35 cM
Alliance:	Dsg4lah page

Strain of Origin:

NB

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: The mutation in the lah allele was identified as an A to C transversion at nucleotide 587 within exon 6. The mutation causes a tyrosine to serine change at amino acid position 196 affecting a potential phosphorylation site. (J:83118) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dsg4 Mutation:	86 strains or lines available

Original:	J:33849 Montagutelli X, et al., Lanceolate hair (lah): a recessive mouse mutation with alopecia and abnormal hair. J Invest Dermatol. 1996 Jul;107(1):20-5
All:	3 reference(s)