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Phenotypes Associated with This Genotype
Genotype
MGI:6472965
Allelic
Composition
GrhprGt(OST383093)Lex/GrhprGt(OST383093)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GrhprGt(OST383093)Lex mutation (1 available); any Grhpr mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• both males and females exhibit an increase in urinary oxalate excretion, with males excreting more urinary oxalate than females
• however, mice do not show changes in urinary glycolate levels
• males fed a 1% hydroxyproline diet exhibit renal oxalosis

renal/urinary system
• both males and females exhibit an increase in urinary oxalate excretion, with males excreting more urinary oxalate than females
• however, mice do not show changes in urinary glycolate levels

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
primary hyperoxaluria type 2 DOID:0111671 OMIM:260000
J:283585


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory