Phenotypes Associated with This Genotype

Genotype
MGI:6459277

• Allelic Composition: Cc2d1a^tm1.1Thkn/Cc2d1a^tm1.1Thkn; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:236761 )

• Background Sensitivity: all mice on a mixed background die within 12 hours of birth compared with mice on a background with increased C57BL/6 that die at birth

respiratory system

respiratory distress ( J:236761 )

• severe in 4 of 12 mice at birth

homeostasis/metabolism

cyanosis ( J:236761 )

• Background Sensitivity: in 4 of 12 mice on a mixed background at birth compared with 5 of 5 mice on a background with increased C57BL/6