Phenotypes Associated with This Genotype

Genotype
MGI:6459276

• Allelic Composition: Cc2d1a^tm1.2Thkn/Cc2d1a^tm1.2Thkn
• Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:236761 )

• mice die after birth

respiratory system

respiratory distress ( J:236761 )

• severe at birth

homeostasis/metabolism

cyanosis ( J:236761 )

• at birth

cellular

abnormal cell morphology ( J:236761 )

• mouse embryonic fibroblasts exhibit increased endo/lysosomal organelles compared with control cells

• however, large multi-membrane structures are not observed