Phenotypes Associated with This Genotype

Genotype
MGI:6196105

• Allelic Composition: F9^em3Dlli/Y
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood coagulation ( J:262204 )

♂ • mice lose more than 10 times the volume of blood lost by wild-type controls after tail-clip

increased partial thromboplastin time ( J:262204 )

♂ • activated partial thromboplastin time is prolonged in 8 week old mice

♂ • however, average prothrombin time is normal

abnormal susceptibility to injury induced morbidity/mortality ( J:262204 )

♂ • survival rate is decreased in the 2 days after the tail-clip challenge

mortality/aging

abnormal susceptibility to injury induced morbidity/mortality ( J:262204 )

♂ • survival rate is decreased in the 2 days after the tail-clip challenge

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hemophilia B		DOID:12259	OMIM:306900	J:262204