About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6192108
Allelic
Composition
Tg(Ela1-Tgfa)150Bri/0
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ela1-Tgfa)150Bri mutation (0 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (155 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• 100% of mice develop pancreatic tumors within 120 days after birth
• pancreatic carcinomas display a ductal phenotype, grow invasively into surrounding tissue, and metastasize

neoplasm
• 100% of mice develop pancreatic tumors within 120 days after birth
• pancreatic carcinomas display a ductal phenotype, grow invasively into surrounding tissue, and metastasize
• pancreatic carcinomas metastasize to liver and lung

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
pancreatic carcinoma DOID:4905 OMIM:260350
J:67389


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/08/2020
MGI 6.15
The Jackson Laboratory