Phenotypes for Adam10 Hr Tg(Dct-lacZ)A12Jkn MGI:6163724 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adam10^Pied/Adam10⁺ Hr^hr/Hr^hr Tg(Dct-lacZ)A12Jkn/0
Genetic Background	involves: C3HeB/FeJ * C57BL/6 * CBA * HRA/SkhKcl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam10^Pied mutation (0 available); any Adam10 mutation (36 available)
Hr^hr mutation (17 available); any Hr mutation (87 available)
Tg(Dct-lacZ)A12Jkn mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal melanocyte morphology ( J:262499 )

• groups of melanocytes are observed at 3 months unlike in Hr^Hr homozygotes

• at 5 months, mice exhibit large groups of melanocytes with melanin deposition in the epidermis unlike Hr^Hr homozygotes

increased melanocyte number ( J:262499 )

• in the skin

integument

hairless ( J:262499 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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