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Phenotypes Associated with This Genotype
Genotype
MGI:6161737
Allelic
Composition		 Baxtm1Sjk/Baxtm1Sjk
Sp9tm1.1Zyan/Sp9tm1.1Zyan
Genetic
Background		 involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
Sp9tm1.1Zyan mutation (0 available); any Sp9 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:238868 )
N
• striatal cell death seen in single mutant SP9 KO mice is nearly absent in the Sp9;Bax/ double mutants at P3
decreased striatum size ( J:238868 )
• at P15, mutant striatum is larger in double mutants than single SP9 KO mice, but smaller than wild-type controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory