Phenotypes Associated with This Genotype

Genotype
MGI:6159937

• Allelic Composition: Pnldc1^em2Nkn/Pnldc1^em2Nkn
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

small testis ( J:262084 )

♂ • approximately half of normal size

arrest of spermatogenesis ( J:262084 )

♂ • at both meiotic and post-meiotic phases

♂ • no sperm in epididymis

male infertility ( J:262084 )

♂ • no sperm in epididymis

endocrine/exocrine glands

small testis ( J:262084 )

♂ • approximately half of normal size

cellular

abnormal DNA methylation ( J:262084 )

♂ • significantly impaired DNA methylation of types A and Gf LINE-1 genes in germ cells of 10-day old mice