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Phenotypes Associated with This Genotype
Genotype
MGI:6159882
Allelic
Composition
Igsf8tm1.2Osb/Igsf8tm1.2Osb
Genetic
Background
involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igsf8tm1.2Osb mutation (0 available); any Igsf8 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• surprisingly, females are healthy and exhibit no fertilization defect in vitro or in vivo
• eggs are morphologically normal and show no defects in plasma membrane binding or the sperm-egg fusion step
• eggs retain normal protein levels and localization of CD9 on their surface, resulting in normal microvilli formation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory