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Phenotypes Associated with This Genotype
Genotype
MGI:6106863
Allelic
Composition
Nlrp9bem1Flv/Nlrp9bem1Flv
Genetic
Background
C57BL/6N-Nlrp9bem1Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp9bem1Flv mutation (0 available); any Nlrp9b mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increased sensitivity to and pathology of oral rotavirus inoculation
• after oral rotavirus inoculation of 8 day old pups
• elevated viral load in intestinal epithelial cells (IECs)
• fecal antigen shedding

mortality/aging
• increased sensitivity to and pathology of oral rotavirus inoculation
• after oral rotavirus inoculation of 8 day old pups
• elevated viral load in intestinal epithelial cells (IECs)
• fecal antigen shedding

cellular
• of intestinal epithelial cells (IECs) after oral rotavirus inoculation of 8 day old pups

digestive/alimentary system
• increased occurrence after oral rotavirus inoculation of 8 day old pups


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory