About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5908863
Allelic
Composition
Ssu2tm1.1Xmx/Ssu2tm1.1Xmx
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ssu2tm1.1Xmx mutation (0 available); any Ssu2 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• abnormal collagenous attachment to the gum
• narrowed dental pulp cavities
• increased number of pulpal cells
• significantly increased numbers of odontoblasts in the pulp cavity
• increased dentin thickness
• anomalies in the number and organization of dentinal tubules
• dysplasia of the mineralized dentin
• mineralized dentin width is higher
• reduced width of the predentin zone
• abnormal tooth attrition whether fed normal diet or a soft diet

growth/size/body
• abnormal collagenous attachment to the gum
• narrowed dental pulp cavities
• increased number of pulpal cells
• significantly increased numbers of odontoblasts in the pulp cavity
• increased dentin thickness
• anomalies in the number and organization of dentinal tubules
• dysplasia of the mineralized dentin
• mineralized dentin width is higher
• reduced width of the predentin zone
• abnormal tooth attrition whether fed normal diet or a soft diet

skeleton
• abnormal collagenous attachment to the gum
• narrowed dental pulp cavities
• increased number of pulpal cells
• significantly increased numbers of odontoblasts in the pulp cavity
• increased dentin thickness
• anomalies in the number and organization of dentinal tubules
• dysplasia of the mineralized dentin
• mineralized dentin width is higher
• reduced width of the predentin zone
• abnormal tooth attrition whether fed normal diet or a soft diet

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
dentin dysplasia DOID:701 OMIM:125400
OMIM:125420
J:240559


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/27/2018
MGI 6.13
The Jackson Laboratory