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Phenotypes Associated with This Genotype
Genotype
MGI:5908862
Allelic
Composition
Ssu2tm1.1Xmx/Ssu2+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ssu2tm1.1Xmx mutation (0 available); any Ssu2 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• abnormal collagenous attachment to the gum
• intermediately narrowed dental pulp cavities
• increased number of pulpal cells
• intermediate increased thickness
• mineralized dentin width is higher
• reduced width of the predentin zone
• intermediate abnormal tooth attrition whether fed normal diet or a soft diet

growth/size/body
• abnormal collagenous attachment to the gum
• intermediately narrowed dental pulp cavities
• increased number of pulpal cells
• intermediate increased thickness
• mineralized dentin width is higher
• reduced width of the predentin zone
• intermediate abnormal tooth attrition whether fed normal diet or a soft diet

skeleton
• abnormal collagenous attachment to the gum
• intermediately narrowed dental pulp cavities
• increased number of pulpal cells
• intermediate increased thickness
• mineralized dentin width is higher
• reduced width of the predentin zone
• intermediate abnormal tooth attrition whether fed normal diet or a soft diet

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
dentin dysplasia DOID:701 OMIM:125400
OMIM:125420
J:240559


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory