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Phenotypes Associated with This Genotype
Genotype
MGI:5897563
Allelic
Composition
Grm6nob8/Grm6nob8
Genetic
Background
CBA/CaJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm6nob8 mutation (1 available); any Grm6 mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• The a-wave is normal, but the scotopic b-wave is reduced although not abolished, with prominant high frequency oscillatory potentials, and the photopic b-wave is reduced nearly to the levels caused by null alleles. This point mutation causes the protein to have decreased glycosylation and mislocalization to the retinal bipolar cell soma instead of the dendritic tips.

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
congenital stationary night blindness 1B DOID:0110865 OMIM:257270
J:240996


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory