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Phenotypes Associated with This Genotype
Genotype
MGI:5825063
Allelic
Composition
Tg(BAC144D14)5A2Masu/0
Genetic
Background
B6J.Cg-Tg(BAC144D14)5A2Masu
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• P7 interscapular brown adipose tissue depots are heavier as a proportion of body weight by 60%
• interscapular brown adipose tissue depots show increased cellularity
• retroperitoneal white adipose tissue shows an abundance of smaller adipocytes with a multilocular appearance
• P7 interscapular brown fat depots show increased cellularity and mitochondrial DNA content
• P7 interscapular brown adipose tissue depots are heavier as a proportion of body weight by 60%
• reduction in weight of mesenteric, inguinal, and retroperitoneal white adipose tissue depots relative to total body weight

behavior/neurological
• mice consume significantly less standard chow than wild-type mice

growth/size/body
• newborns are lighter
• males and females are lighter at 10 weeks of age
• fetuses are lighter at E18.5

homeostasis/metabolism
• hypoglycemia in the fed state
• basal body temperature is elevated

nervous system
• increase in brain weight/body weight ratio in newborns

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Silver-Russell syndrome DOID:14681 OMIM:180860
J:232408


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory