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Phenotypes Associated with This Genotype
Genotype
MGI:5791914
Allelic
Composition
Tg(Neurod2-Smo*A1)199Jols/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Neurod2-Smo*A1)199Jols mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• at 8 months of age, 50% of mice have to be sacrificed due to tumor burden

neoplasm
• mice start developing medullobalstoma at around 4 months of age
• 38% medulloblastoma incidence

nervous system
• mice start developing medullobalstoma at around 4 months of age
• 38% medulloblastoma incidence

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
medulloblastoma DOID:0050902 OMIM:155255
J:221990


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory