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Phenotypes Associated with This Genotype
Genotype
MGI:5790977
Allelic
Composition
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor
Ptentm1Mro/Ptentm1Mro
Trp53tm1Brn/Trp53tm1Brn
Genetic
Background
involves: 129P2/OlaHsd * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (8 available); any Gt(ROSA)26Sor mutation (765 available)
Ptentm1Mro mutation (1 available); any Pten mutation (78 available)
Trp53tm1Brn mutation (17 available); any Trp53 mutation (210 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice injected with an adenovirus expressing cre recombinase (Ad-Cre) into the left ventricle exhibit a 33.3% incidence of glioma
• in left ventricle Ad-cre injected mice
• in left ventricle Ad-cre injected mice

nervous system
• mice injected with an adenovirus expressing cre recombinase (Ad-Cre) into the left ventricle exhibit a 33.3% incidence of glioma
• in left ventricle Ad-cre injected mice
• in left ventricle Ad-cre injected mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
high grade glioma DOID:3070 OMIM:PS137800
J:229481


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory