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Phenotypes Associated with This Genotype
Genotype
MGI:5767781
Allelic
Composition
Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic
Background
C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay
Cell Lines EPD0663_5_A10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad9atm1.1(KOMP)Wtsi mutation (0 available); any Rad9a mutation (27 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
IMPC - BCM (J:211773)
MGI
• yolk sac vasculature is an un-remodeled, primitive plexus (J:237214)
• the heart tube remains linear without undergoing further looping process compared to the left/right atrium and ventricles that form in controls at E9.5

craniofacial

embryo
IMPC - BCM (J:211773)
MGI
• yolk sac vasculature is an un-remodeled, primitive plexus (J:237214)
IMPC - BCM (J:211773)
MGI
• severe developmental defects at E9.5 (J:237214)
IMPC - BCM (J:211773)
MGI
• embryos do not turn at E9.5 (J:237214)
• the ventral midgut region remains open at E9.5
• posterior part of the embryo is severely dysmorphic at E9.5
• anterior neural folds are still open at E9.5
IMPC - BCM

growth/size/body

integument
IMPC - BCM

mortality/aging

nervous system


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory