Phenotypes for Smarca2 Smarca4 MGI:5763443 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smarca2^tm1Mya/Smarca2^tm1Mya Smarca4^tm1Mag/Smarca4⁺
Genetic Background	involves: 129S/Sv * 129S2/SvPas * C57BL/6J * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarca2^tm1Mya mutation (0 available); any Smarca2 mutation (90 available)
Smarca4^tm1Mag mutation (1 available); any Smarca4 mutation (109 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:132091 )

• one female develops a mammary tumor at 14 months of age

integument

increased mammary gland tumor incidence ( J:132091 )

• one female develops a mammary tumor at 14 months of age

neoplasm

increased mammary gland tumor incidence ( J:132091 )

• one female develops a mammary tumor at 14 months of age

increased hemangiosarcoma incidence ( J:132091 )

• one male develops a hemangiosarcoma at 16 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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