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Phenotypes Associated with This Genotype
Genotype
MGI:5762655
Allelic
Composition		 Gfertm1.1Crg/Gfertm1.1Crg
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfertm1.1Crg mutation (0 available); any Gfer mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
abnormal hepatocyte morphology ( J:227242 )
• hepatocytes transfected with a cre-expressing adenovirus exhibit increased lipid accumulation compared with control cells

cellular
abnormal mitochondrial chromosome morphology ( J:227242 )
• increased mitochondrial damage in hepatocytes transfected with a cre-expressing adenovirus
oxidative stress ( J:227242 )
• in hepatocytes transfected with a cre-expressing adenovirus

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory