About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5708536
Allelic
Composition
Enamtm1.1Jcch/Enam+
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Enamtm1.1Jcch mutation (1 available); any Enam mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• some irregularity of the ameloblast cell layers, specifically homogeneity and continuity, among molars
• mandibular incisors show disturbed ameloblasts resulting in cyst formation within the enamel organ beginning in late secretory stage
• organized rods are present in incisors but they are spaced further apart

skeleton
• some irregularity of the ameloblast cell layers, specifically homogeneity and continuity, among molars
• mandibular incisors show disturbed ameloblasts resulting in cyst formation within the enamel organ beginning in late secretory stage
• organized rods are present in incisors but they are spaced further apart

growth/size/body
• some irregularity of the ameloblast cell layers, specifically homogeneity and continuity, among molars
• mandibular incisors show disturbed ameloblasts resulting in cyst formation within the enamel organ beginning in late secretory stage
• organized rods are present in incisors but they are spaced further apart

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amelogenesis imperfecta type 1B DOID:0110052 OMIM:104500
J:223123


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory