Phenotypes Associated with This Genotype

Genotype
MGI:5659878

• Allelic Composition: Kras^tm4Tyj/Kras⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:124682 )

• mice inoculated with an adenovirus expressing cre recombinase (ad-cre) by inhalation have a median survival of 24 weeks after ad-cre inoculation

neoplasm

increased lung adenocarcinoma incidence ( J:124682 )

• mice inoculated with ad-cre by inhalation develop lung tumors with high multiplicity, long latency, and low aggressiveness

• all tumors of ad-cre inoculated mice are adenocarincomas

• metastasis or local invasion is not seen in ad-cre inoculated mice

respiratory system

increased lung adenocarcinoma incidence ( J:124682 )

• mice inoculated with ad-cre by inhalation develop lung tumors with high multiplicity, long latency, and low aggressiveness

• all tumors of ad-cre inoculated mice are adenocarincomas

• metastasis or local invasion is not seen in ad-cre inoculated mice