Phenotypes Associated with This Genotype

Genotype
MGI:5631068

• Allelic Composition: Dnmt3a^{tm1b(KOMP)Wtsi}/Dnmt3a⁺
• Genetic Background: C57BL/6N-Dnmt3a^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0332_1_A05

Data Sources

IMPC Data for Dnmt3a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - JAX

behavior/neurological

convulsive seizures ( J:211773 )

♀

IMPC - JAX

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

nervous system

convulsive seizures ( J:211773 )

♀

IMPC - JAX

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - JAX