Phenotypes Associated with This Genotype

Genotype
MGI:5608670

• Allelic Composition: Myo5a^d-l35J/Myo5a^d-l35J
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:216347 )

ataxia ( J:216347 )

• homozygotes display a sprawling ataxia with an inability to right themselves

impaired balance ( J:216347 )

integument

diluted coat color ( J:216347 )

• the diluted coat color is evident as soon as the coat comes in and resembles the misty mutation on the C57BL/6J background

mortality/aging

lethality at weaning, complete penetrance ( J:216347 )

• all homozygotes die by 5 weeks of age

pigmentation

diluted coat color ( J:216347 )

• the diluted coat color is evident as soon as the coat comes in and resembles the misty mutation on the C57BL/6J background

growth/size/body

decreased body size ( J:216347 )

• homozygotes are smaller than normal littermates