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Phenotypes Associated with This Genotype
Genotype
MGI:5566667
Allelic
Composition		 Mtch2tm2Atgr/Mtch2tm2.1Atgr
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtch2tm2.1Atgr mutation (0 available); any Mtch2 mutation (24 available)
Mtch2tm2Atgr mutation (0 available); any Mtch2 mutation (24 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
liver failure ( J:209127 )
• resistant to liver failure caused by intraperitoneal injection of anti-FAS antibody
• recruitment of tBID to liver mitochondria is reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory