Mouse Genome Informatics
tg
    Tg(SERPINA1*E342K)Z1.01Slcw/Tg(SERPINA1*E342K)Z1.01Slcw
involves: C57BL/6 * ICR
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice show elevations in liver enzymes such as alanine transaminase and aspartate aminotransferase

liver/biliary system
• mice show liver fibrosis around 4 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Alpha-1-Antitrypsin Deficiency 613490 J:208016