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Phenotypes Associated with This Genotype
Genotype
MGI:5562921
Allelic
Composition
Tg(SERPINA1*E342K)Z1.01Slcw/Tg(SERPINA1*E342K)Z1.01Slcw
Genetic
Background
involves: C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice show elevations in liver enzymes such as alanine transaminase and aspartate aminotransferase

liver/biliary system
• mice show liver fibrosis around 4 months of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Alpha-1-Antitrypsin Deficiency; A1ATD 613490 J:208016


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory