Phenotypes Associated with This Genotype

Genotype
MGI:5562291

• Allelic Composition: Habp2^tm1Lex/Habp2^tm1Lex
• Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to induced morbidity/mortality ( J:207454 )

• 1 of 11 mice die following bile duct ligation compared with 6 of 11 wild-type mice

liver/biliary system

liver inflammation ( J:207454 )

• following bile duct ligation

liver fibrosis ( J:207454 )

• following bile duct ligation or CCl4 treatment

homeostasis/metabolism

abnormal response to injury ( J:207454 )

• following bile duct ligation, mice exhibit decreased lethality and increased liver fibrosis, injury and inflammation compared with wild-type mice

immune system

liver inflammation ( J:207454 )

• following bile duct ligation