Mouse Genome Informatics
tg
    Tg(Utg-TAg)7736Fjd/?
involves: FVB
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• succumb at 16-20 weeks

respiratory system
• areas of hyperplasia of the bronchiolar epithelium are seen by 2 months of age

tumorigenesis
• mutants develop multifocal pulmonary adenocarcinoma of the lung and succumb at 16-20 weeks of age
• bronchiolar epithelium shows areas of hyperplasia by 2 months of age, tumor foci are seen at 3 months and majority of lung is composed of transformed cells 4 weeks later

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:70785