Phenotypes Associated with This Genotype

Genotype
MGI:5546336

• Allelic Composition: Fst^tm1Zuk/Fst^tm1Zuk; Wfikkn1^tm1.1Sjl/Wfikkn1^tm1.1Sjl
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Axial skeleton patterning defects in Wfikkn1^tm1.1Sjl/Wfikkn1^tm1.1Sjl, Wfikkn1^tm1.1Sjl/Wfikkn1^tm1.1Sjl Fst^tm1Zuk/Fst^tm1Zuk, Gdf11^tm1Sjl/Gdf11⁺ and Gdf11^tm1Sjl/Gdf11^tm1Sjl mice.

skeleton

abnormal cervical rib ( J:201148 )

• mice have cervical ribs on one side or both sides

decreased rib number ( J:201148 )

• both 13th ribs are missing

• most mice have 6 or 6.5 attached ribs

increased rib number ( J:201148 )

• mice have cervical ribs on one side or both sides

decreased thoracic vertebrae number ( J:201148 )

• all mice have only 12 thoracic vertebrae

decreased lumbar vertebrae number ( J:201148 )

• one mouse had only 4 lumbar vertebrae