Mouse Genome Informatics
ht
    Scn1atm1Kea/Scn1a+
(C57BL/6J x 129S6/SvEvTac-Scn1atm1Kea)F1
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• Background Sensitivity: mice on a background containing C57BL/6J exhibit premature death with 50% of mice dying by 1 month of age unlike mice on a coisogenic 129S6/SvEvTac background

behavior/neurological
• Background Sensitivity: mice on a background containing C57BL/6J exhibit spontaneous seizures unlike mice on a coisogenic 129S6/SvEvTac background

nervous system
• Background Sensitivity: mice on a background containing C57BL/6J exhibit spontaneous seizures unlike mice on a coisogenic 129S6/SvEvTac background

Mouse Models of Human Disease
OMIM IDRef(s)
Epileptic Encephalopathy, Early Infantile, 6; EIEE6 607208 J:203040