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Phenotypes Associated with This Genotype
Genotype
MGI:5523889
Allelic
Composition
Scn1atm2.1Kzy/Scn1atm2.1Kzy
Tg(Pvalb-cre)1Tama/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn1atm2.1Kzy mutation (1 available); any Scn1a mutation (73 available)
Tg(Pvalb-cre)1Tama mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all animals die before P30

behavior/neurological
• develops around P14
• mice are physically normal for first week postnatal, but around P10 develop spontaneous generalized convulsive seizures

nervous system
• mice are physically normal for first week postnatal, but around P10 develop spontaneous generalized convulsive seizures

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Dravet syndrome DOID:0080422 OMIM:607208
J:202863


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory