Phenotypes Associated with This Genotype

Genotype
MGI:5522969

• Allelic Composition: Hoxd^tm1.1Ssp/Hoxd^tm1.1Ssp
• Genetic Background: involves: 129 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:198638 )

♀N • no gross uterine abnormalities are detected

abnormal vas deferens morphology ( J:198638 )

♂ • occasional minor coiling near the epididymal junction

reduced female fertility ( J:198638 )

♀ • show evidence of subfertility

♀ • pups in litters born to homozygous females often die postnatally with no milk spot or are severely runted

decreased litter size ( J:198638 )

♀ • seen when mutant females when mated to wild-type males

♀ • pups in litters born to homozygous females often die postnatally with no milk spot or are severely runted

male infertility ( J:198638 )

♂ • males fail to produce vaginal plugs when mated with wild-type females

behavior/neurological

failure of copulatory plug deposition ( J:198638 )

♂ • males fail to produce vaginal plugs when mated with wild-type females