Mouse Genome Informatics
cx
    Tg(CTSG-RARA/ZBTB16)#Sjch/0
Tg(CTSG-ZBTB16/RARA)#Sjch/0

Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hematopoietic system
• impairment of normal hematopoiesis

tumorigenesis
• mutants develop myeloid leukemia resembling human t(11;17) acute promyelocytic leukemia, showing an accumulation of immature myeloblastic cells in hematopoietic tissues and infiltration of nonhematopoietic organs, including the liver, lung, gastrointestinal tract, and kidney

Mouse Models of Human Disease
OMIM IDRef(s)
Acute Promyelocytic Leukemia; APL 612376 J:194312