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Phenotypes Associated with This Genotype
Genotype
MGI:5508780
Allelic
Composition		 Onecut1tm1Flem/Onecut1tm1Flem
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Onecut1tm1Flem mutation (0 available); any Onecut1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal pancreas development ( J:83754 )
• pancreatic buds smaller and less lobulated by E12.5
• dorsal bud more elongated and flattened with about half the normal number of cells at E10.75
• at the same time the ventral pancreas is not visible

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory