Mouse Genome Informatics
hm
    Myh9tm1.1(MYH9*)Mjk/Myh9tm1.1(MYH9*)Mjk
B6.129-Myh9tm1.1(MYH9*)Mjk
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hematopoietic system
• contain Myh9 aggregates
• with neutrophil inclusions in the bone marrow
• increased diameter
• macrothrombocytopenia

homeostasis/metabolism

renal/urinary system
• focal segmental glomerulosclerosis and focal global glomerulosclerosis beginning at 4 months

immune system
• contain Myh9 aggregates

Mouse Models of Human Disease
OMIM IDRef(s)
Epstein Syndrome 153650 J:175367
Fechtner Syndrome; FTNS 153640 J:175367
May-Hegglin Anomaly; MHA 155100 J:175367
Sebastian Syndrome; SBS 605249 J:175367