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Phenotypes Associated with This Genotype
Genotype
MGI:5499734
Allelic
Composition
Myh9tm1.1(MYH9*)Mjk/Myh9+
Genetic
Background
B6.Cg-Myh9tm1.1(MYH9*)Mjk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh9tm1.1(MYH9*)Mjk mutation (0 available); any Myh9 mutation (208 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• with mild inflammatory cellular infiltration
• liquefaction of lens fibers
• bilateral in some mice with swelling, lens epithelial proliferation and degeneration, and liquefaction of lens fibers
• lens epithelial proliferation and degeneration
• liquefaction of lens fibers
• mild inflammatory cellular infiltration

hematopoietic system
• contain Myh9 aggregates
• increased diameter
• macrothrombocytopenia

hearing/vestibular/ear
• progressive hearing loss with age

homeostasis/metabolism

renal/urinary system

immune system
• contain Myh9 aggregates
• mild inflammatory cellular infiltration

cardiovascular system
• with mild inflammatory cellular infiltration


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory