Mouse Genome Informatics
ht
    Myh9tm1.1(MYH9*)Mjk/Myh9+
B6.Cg-Myh9tm1.1(MYH9*)Mjk
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
• with mild inflammatory cellular infiltration
• liquefaction of lens fibers
• bilateral in some mice with swelling, lens epithelial proliferation and degeneration, and liquefaction of lens fibers
• lens epithelial proliferation and degeneration
• liquefaction of lens fibers
• mild inflammatory cellular infiltration

hematopoietic system
• contain Myh9 aggregates
• increased diameter
• macrothrombocytopenia

hearing/vestibular/ear
• progressive hearing loss with age

homeostasis/metabolism

renal/urinary system

immune system
• contain Myh9 aggregates
• mild inflammatory cellular infiltration

cardiovascular system
• with mild inflammatory cellular infiltration

Mouse Models of Human Disease
OMIM IDRef(s)
Epstein Syndrome 153650 J:175367
Fechtner Syndrome; FTNS 153640 J:175367
May-Hegglin Anomaly; MHA 155100 J:175367
Sebastian Syndrome; SBS 605249 J:175367