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Phenotypes Associated with This Genotype
Genotype
MGI:5491872
Allelic
Composition
L1camtm4.1Vlem/Y
Genetic
Background
either: 129S4.129S2-L1camtm4.1Vlem or B6.129S4-L1camtm4.1Vlem
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
L1camtm4.1Vlem mutation (0 available); any L1cam mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice exhibit normal survival

behavior/neurological
N
• mice exhibit normal spatial memory
• on an accelerating rotarod
• however, mice are able to remain on an immobile rod without falling

nervous system
N
• mice do not exhibit hydrocephalus and unmyelinated and myelinated axons
• reduced number of branches and neurite total or longest neurite lengths when cultured on L1-Fc substrate
• reduced number of branches when cultured on laminin substrate


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory