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Phenotypes Associated with This Genotype
Genotype
MGI:5491050
Allelic
Composition
Prnptm1Cwe/Prnptm1Cwe
Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp
Genetic
Background
involves: 129S7/SvEvBrd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prnptm1Cwe mutation (29 available); any Prnp mutation (87 available)
Tg(Prnp*P101L)2866Sbp mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mean age for development of neurologic disease is 85 +/- 2 days

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Gerstmann-Straussler-Scheinker syndrome DOID:4249 OMIM:137440
J:136434


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory