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Phenotypes Associated with This Genotype
Genotype
MGI:5490240
Allelic
Composition		 Fkbp1atm1.1Shou/Fkbp1atm1Zuk
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp1atm1.1Shou mutation (0 available); any Fkbp1a mutation (12 available)
Fkbp1atm1Zuk mutation (0 available); any Fkbp1a mutation (12 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:195489 )
• all mutants survive through birth, but all die within 1 month of birth (proposed to be due to defective thymus development)

cardiovascular system
cardiovascular system phenotype ( J:195489 )
N
• animals show normal ventricular chamber formation; normal trabeculation and compaction in ventricles are observed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory