Phenotypes Associated with This Genotype

Genotype
MGI:5489760

• Allelic Composition: Gja8^R205G/Gja8^R205G
• Genetic Background: B6.Cg-Gja8^R205G

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Dense nuclear cataracts in Gja8^R205G/Gja8^R205G and Gja8^R205G/Gja8^R205G Gja3^tm1Scr/Gja3^tm1Scr mice but degenerating peripheral lens fibers only in Gja8^R205G/Gja8^R205G mice

vision/eye

vacuolated lens ( J:195727 )

• aberrant vacuole-like structures in the lens periphery

nuclear cataracts ( J:195727 )

• dense

small lens ( J:195727 )

microphthalmia ( J:195727 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 1 multiple types		DOID:0110231	OMIM:116200	J:195727