Mouse Genome Informatics
hm
    Slc27a4pskn/Slc27a4pskn
involves: FVB
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• within a few hours of birth

integument
• aberrant epidermal differentiation
• massive
• change in patterning, size and distribution
• increased number of cell layers
• mice are born with smooth, tight and shiny skin
• skin cracking upon stretching
• exterior surface of the skin and the epidermal-dermal junction is flattened
• at birth
• at birth

behavior/neurological
• newborns are immobilized in fetal position due to tight skin

cellular
• on the toes and tip of the tail in some mice at birth

craniofacial

digestive/alimentary system

skeleton

Mouse Models of Human Disease
OMIM IDRef(s)
Ichthyosis Prematurity Syndrome; IPS 608649 J:194779