Mouse Genome Informatics
ht
    Ube3atm1Alb/Ube3a+
involves: 129S7/SvEvBrd * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
homeostasis/metabolism
• mice with maternal deficiency (inheriting the null allele from the mother) exhibit increased epinephrine levels in the midbrain
• mice with maternal deficiency exhibit increased dopamine levels in the striatum and cortex
• DOPAC levels are increased in the striatum and midbrain
• mice with maternal deficiency exhibit increased 5HT (serotonin) levels in the frontal cortex and striatum

nervous system
• mice with maternal deficiency exhibit increased dopamine levels in the striatum and cortex
• DOPAC levels are increased in the striatum and midbrain

Mouse Models of Human Disease
OMIM IDRef(s)
Angelman Syndrome; AS 105830 J:190050