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Phenotypes Associated with This Genotype
Genotype
MGI:5449076
Allelic
Composition
Tg(TNF)3647Gkl/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(TNF)3647Gkl mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• from isolated bone marrow-derived stromal cells
• at 2 to 3 months
• at 4 months
• reduced bone formation rate
• reduced mineral apposition rate

immune system
• at 2 to 3 months

cellular
• from isolated bone marrow-derived stromal cells

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
rheumatoid arthritis DOID:7148 OMIM:180300
J:190204


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory