Phenotypes for Kdm6a MGI:5448831 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Kdm6a^tm1.2Kaig/Y
Genetic Background	involves: 129S4/SvJaeSor

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6a^tm1.2Kaig mutation (0 available); any Kdm6a mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Execenphaly in Kdm6a^tm1.2Kaig/Y males

mortality/aging

• mice die around birth

embryo

embryo phenotype ( J:190157 )

N	• mice exhibit normal mesoderm development

abnormal neural tube closure ( J:190157 )

respiratory system

atelectasis ( J:190157 )

• lungs are not inflated at birth

respiratory distress ( J:190157 )

• inability to breath

nervous system

abnormal neural tube closure ( J:190157 )

exencephaly ( J:190157 )

• in some mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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