• both adrenal and brain tumors resemble neuroblastomas composed of small, densely packed, undifferentiated cells with scant cytoplasm

• no other organ besides the brain and adrenal glands develop a tumor

• adrenal glands develop tumors resembling neuroblastomas

• mutants develop brain tumors, with onset of tumors varying from 15 weeks to 8.5 months

• tumors are found on the ventral aspect of the brain, centered about the midbrain and rostral brainstem

• tumor bearing mutants exhibit motor difficulties, a hunched posture, and enlarged head