Mouse Genome Informatics
ht
    Sox7tm1.1Dsco/Sox7+
involves: 129/SvEv * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
muscle
• in some cases the gallbladder is fused to the underside of the anterior diaphragm
• Background Sensitivity: around 14% of mice (10 of 71, age P28 to adult) on a mixed 129 and C57BL/6 background have congenital diaphragmatic hernia located directly behind the sternum in the ventral midline; hernias are not seen in mice on a congenic C57BL/6 background
• in severe cases the gallbladder and a pedunculated portion of the liver are found in the thoracic cavity

liver/biliary system
• in some cases the gallbladder is fused to the underside of the anterior diaphragm

endocrine/exocrine glands
• in some cases the gallbladder is fused to the underside of the anterior diaphragm

Mouse Models of Human Disease
OMIM IDRef(s)
Diaphragmatic Hernia, Congenital 142340 J:187416