Phenotypes Associated with This Genotype

Genotype
MGI:5435704

• Allelic Composition: Shank3^tm1.1Geno/Shank3^tm1.1Geno
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal response to novelty ( J:293942 )

• reduced discrimination index in virtual object recognition test with stationary shapes, whether or not moving different shapes or moving identical shapes were presented in intertrial delay

abnormal response to novel object ( J:293942 )

• reduced discrimination index in novel object recognition test

integument

skin lesions ( J:186719 )

• display head or neck lesions at 3 months of age