Mouse Genome Informatics
cn
    Fktntm1Kcam/Fktntm1Kcam
Tg(Ckmm-cre)5Khn/?

involves: 129S/SvEv * FVB
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
muscle
• signs of dystrophic disease at 12 weeks of age
• central nucleation in muscle fibers
• variable fiber size
• hypercontracted fibers

homeostasis/metabolism
• elevated serum creatine kinase at 12 weeks of age

behavior/neurological
• reduced running times on a treadmill

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 4; MDDGA4 253800 J:187144