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Phenotypes Associated with This Genotype
Genotype
MGI:5435675
Allelic
Composition
Fktntm1Kcam/Fktntm1Kcam
Tg(Ckmm-cre)5Khn/?
Genetic
Background
involves: 129S/SvEv * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fktntm1Kcam mutation (1 available); any Fktn mutation (11 available)
Tg(Ckmm-cre)5Khn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• signs of dystrophic disease at 12 weeks of age
• central nucleation in muscle fibers
• variable fiber size
• hypercontracted fibers

homeostasis/metabolism
• elevated serum creatine kinase at 12 weeks of age

behavior/neurological
• reduced running times on a treadmill


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory