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Phenotypes Associated with This Genotype
Genotype
MGI:5432230
Allelic
Composition
Tg(Dct-Grm1)ESzc/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• hyperproliferation in the pinnae and tail
• pinnae, tail, limbs, around snout, eyelid and submandibular and inguinal lymph nodes
• hyperpigmented lesions
• hyperpigmented lesions

neoplasm
• flat hyperpigmented lesions develop into raised melanomas on the pinnae and tail
• occasionally on the eye lid

immune system

cellular
• hyperproliferation in the pinnae and tail

craniofacial
• hyperpigmented lesions

hearing/vestibular/ear
• hyperpigmented lesions

integument
• hyperpigmented lesions
• hyperpigmented lesions
• flat hyperpigmented lesions develop into raised melanomas on the pinnae and tail
• occasionally on the eye lid

limbs/digits/tail
• hyperpigmented lesions

growth/size/body
• hyperpigmented lesions


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory